Players take upon the role of Bishop who has been deployed by Rainbow squad to a French observatory to rescue a group of European Union hostages. The game starts in 2005, before the events of Tom Clancy's Rainbow Six 3: Raven Shield.
The game was marketed as a 'part sequel, part prequel' as the events of the single player campaign occur before and concurrently to the story of Logan Keller (the protagonist players assumed in the first game) as well as continuing on after the events of the first game in the series. The game is the seventh game in the Rainbow Six franchise and the second, and last game in the Vegas sub-series of games in the franchise according to Ubisoft. Tom Clancy's Rainbow Six: Vegas 2 was released on the Xbox 360 and PS3 on March 18, 2008, and the PC on Apand was developed by Ubisoft Montreal Studios.